http://en.wikipedia.org/wiki/Red_blood_cell
This asymmetric phospholipid distribution among the bilayer is the result of the function of several energy-dependent and energy-independent phospholipid transport proteins.
Proteins called “Flippases” move phospholipids from the outer to the inner monolayer,
while others called “floppases” do the opposite operation, against a concentration gradient in an energy dependent manner.
Additionally, there are also “scramblase” proteins that move phospholipids in both directions at the same time, down their concentration gradients in an energy independent manner.
There is still considerable debate ongoing regarding the identity of these membrane maintenance proteins in the red cell membrane.
This asymmetric phospholipid distribution among the bilayer is the result of the function of several energy-dependent and energy-independent phospholipid transport proteins.
Proteins called “Flippases” move phospholipids from the outer to the inner monolayer,
while others called “floppases” do the opposite operation, against a concentration gradient in an energy dependent manner.
Additionally, there are also “scramblase” proteins that move phospholipids in both directions at the same time, down their concentration gradients in an energy independent manner.
There is still considerable debate ongoing regarding the identity of these membrane maintenance proteins in the red cell membrane.
No comments:
Post a Comment