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Saturday, 5 July 2014

Dendritic Cells.

http://en.wikipedia.org/wiki/Phagocyte

Dendritic cells are specialized antigen-presenting cells that have long outgrowths called dendrites,that help to engulf microbes and other invaders.Dendritic cells are present in the tissues that are in contact with the external environment, mainly the skin, the inner lining of the nose, the lungs, the stomach, and the intestines.Once activated, they mature and migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and orchestrate the adaptive immune response.Mature dendritic cells activate T helper cells and cytotoxic T cells.The activated helper T cells interact with macrophages and B cells to activate them in turn. In addition, dendritic cells can influence the type of immune response produced; when they travel to the lymphoid areas where T cells are held they can activate T cells, which then differentiate into cytotoxic T cells or helper T cells.

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