http://en.wikipedia.org/wiki/Dendritic_cell
The blood DCs are typically identified and enumerated in flow cytometry. Three types of DCs have been defined in human blood and these are the CD11c+ myeloid DCs, the CD141+ myeloid DCs and the CD303+ plasmacytoid DCs. This represents the nomenclature proposed by the respective IUIS nomenclature committee Dendritic cells that circulate in blood do not have all the typical features of their counterparts in tissue, i.e. they are less mature and have no dendrites. Still, they can perform complex functions including chemokine-production in CD11c+ myeloid DCs, cross-presentation in CD141+ myeloid DCs and IFNalpha production in CD303+ plasmacytoid DCs.
The blood DCs are typically identified and enumerated in flow cytometry. Three types of DCs have been defined in human blood and these are the CD11c+ myeloid DCs, the CD141+ myeloid DCs and the CD303+ plasmacytoid DCs. This represents the nomenclature proposed by the respective IUIS nomenclature committee Dendritic cells that circulate in blood do not have all the typical features of their counterparts in tissue, i.e. they are less mature and have no dendrites. Still, they can perform complex functions including chemokine-production in CD11c+ myeloid DCs, cross-presentation in CD141+ myeloid DCs and IFNalpha production in CD303+ plasmacytoid DCs.
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