http://en.wikipedia.org/wiki/Insulin
Insulin is a very old protein that may have originated more than one billion years ago.The molecular origins of insulin go at least as far back as the simplest unicellular eukaryotes.Apart from animals, insulin-like proteins are also known to exist in Fungi and Protista kingdoms.Insulin's name is derived from the Latin insula for "island".
The human insulin protein is composed of 51 amino acids, and has a molecular weight of 5808 Da. It is adimer of an A-chain and a B-chain, which are linked together by disulfide bonds.
Insulin is a very old protein that may have originated more than one billion years ago.The molecular origins of insulin go at least as far back as the simplest unicellular eukaryotes.Apart from animals, insulin-like proteins are also known to exist in Fungi and Protista kingdoms.Insulin's name is derived from the Latin insula for "island".
The human insulin protein is composed of 51 amino acids, and has a molecular weight of 5808 Da. It is adimer of an A-chain and a B-chain, which are linked together by disulfide bonds.
High-resolution model of six insulin molecules assembled in a hexamer, highlighting the three fold symmetry, the zinc ion holding it together (pink sphere), and the histidine residues (pink sticks) involved in zinc binding. Inactive insulin is stored in the body as a hexamer, while the active form is the monomer.
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